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Cyclobenzaprine LiverTox NCBI Bookshelf

This is not a complete list of side effects and others may occur. The efficacy of FLEXERIL 5 mg was demonstrated in two seven-day, double-blind, controlled clinical trials enrolling 1405 patients. One study compared FLEXERIL 5 mg and 10 mg t.i.d. to placebo; and a second study compared FLEXERIL 5 mg and 2.5 mg t.i.d. to placebo.

For these reasons, in the elderly, cyclobenzaprine should be used only if clearly needed. In such patients FLEXERIL should be initiated with a 5 mg dose and titrated slowly upward. The overall incidence of adverse reactions among patients in the surveillance program was less than the incidence in the controlled clinical studies. There is also the possibility of becoming psychologically dependent on Flexeril because of the feelings of relaxation. Flexeril on its own may not be as susceptible to creating addiction but when it’s abused, there’s a much greater risk.

It can cause changes in blood pressure, body temperature and lead to a change in behavior. If a person has an overactive thyroid, heart issues or problems with the liver, Flexeril can be risky and should not be taken. If you have muscle spasms or muscle pain and plan to take skeletal muscle relaxants, please work with your healthcare provider to find the one that works best for you. Keep in mind that along with medications for short-term alleviation of pain and discomfort, rest and physical therapy can help with long-term pain relief and function.

What is Cyclobenzaprine (Flexeril) used for?

Do not take more or less of it or take it more often than prescribed by your doctor. Cyclobenzaprine is used with rest, physical therapy, and other measures to relax muscles and relieve pain and discomfort caused by strains, sprains, and other muscle injuries. Cyclobenzaprine is in a class of medications called skeletal muscle relaxants. It works by acting in the brain and nervous system to allow the muscles to relax. Another potential side effect of Flexeril is overdose if an individual takes too much of the drug. Although Flexeril doesn’t produce a euphoric high like many other drugs, people still misuse it due to its relaxing effects; many will increase dosages to amplify those effects.

  • Both medications can cause adverse effects such as dizziness, drowsiness, headache, nausea, and fatigue.
  • In three of these studies there was a significantly greater improvement with FLEXERIL than with diazepam, while in the other studies the improvement following both treatments was comparable.
  • Signs and symptoms of toxicity may develop rapidly after cyclobenzaprine overdose; therefore, hospital monitoring is required as soon as possible.
  • It is also possible for serious cyclobenzaprine side effects to occur, like seizures, heart arrhythmias, heart attack, or stroke.

Many insurance companies require prior authorization for this drug. This means your doctor will need to get approval from your insurance company before your insurance company will pay for the prescription. If you have liver problems, your doctor may do a blood test to monitor how well your liver is working while you take this drug. You should not need a new prescription for this medication to be refilled. Your doctor will write the number of refills authorized on your prescription.

What is Blink Health?

This is marked by a need to use cyclobenzaprine regularly in order to simply function. And when this dependency gets out of hand, Flexeril addiction is possible, which can have long-term implications and health effects that can end up tearing apart your life as you know it. These two dangerous consequences of Flexeril abuse flexeril and weed are exacerbated by the fact that mixing drugs with cyclobenzaprine can make Flexeril addictive and deadly on a whole new level. Taking Flexeril with MAOs puts a person at high risk of a dangerous medical condition. It can occur when Tetracyclic Compounds and MAOIs both raise the level of serotonin too high in the body.

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Cyclobenzaprine starts to relax muscles and relieve muscle spasms about an hour after it is ingested. If it’s almost time for your next dose, skip the missed dose and resume taking drugs on the right schedule. Do not take extra doses at the same time to make up for a missed dose.

Usually, people won’t die from a cyclobenzaprine overdose. There are over 12,000 people in the U.S who will go to the emergency room looking to be treated for Flexeril overdose. A study showed that 209 people who overdosed on Flexeril on its own survived the ordeal. Mixing the drug with other substances, however, has shown to cause accidents leading to death. Zanaflex has the potential to cause hypotension or abnormally low blood pressure. This effect typically manifests as orthostatic hypotension which occurs when a person moves to an upright position after lying down.

Why is this medication prescribed?

If you believe you’re addicted to Flexeril, please don’t put off getting help. It’s important to talk with an addiction treatment specialist as soon as you can. That way, you can find out for sure if what you’re dealing with is an actual addiction.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Using Flexeril with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures. Overdose symptoms may include severe drowsiness, vomiting, fast heartbeats, tremors, agitation, or hallucinations. Do not use Flexeril if you have taken an MAO inhibitor in the past 14 days. Other potential effects of overdosage include any of the symptoms listed under ADVERSE REACTIONS.

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